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Molecular basis of inherited predispositions for tumors
- Source :
- Acta Biochimica Polonica. 49:571-581
- Publication Year :
- 2002
- Publisher :
- Polskie Towarzystwo Biochemiczne (Polish Biochemical Society), 2002.
-
Abstract
- On the basis of literature data and own experience the authors review the current knowledge about the molecular basis of inherited predispositions for tumors. They hypothesize that in the near perspective 5-10 years studies using existing registry data/material and the latest novel technology will allow the identification of the molecular background for the majority of hereditary cancers which will have enormous practical consequences especially for the prevention of malignancies.
- Subjects :
- DNA Repair
Base Pair Mismatch
business.industry
DNA Mutational Analysis
Computational biology
General Biochemistry, Genetics and Molecular Biology
Pedigree
Gene interaction
Neoplasms
Mutation
Cancer research
Humans
Medicine
Genetic Predisposition to Disease
Identification (biology)
Registry data
business
Subjects
Details
- ISSN :
- 1734154X and 0001527X
- Volume :
- 49
- Database :
- OpenAIRE
- Journal :
- Acta Biochimica Polonica
- Accession number :
- edsair.doi.dedup.....bedbe03f9ad3551300461cde3e229a8d