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Sensitive line probe assay that simultaneously detects mutations conveying resistance to lamivudine and adefovir

Authors :
Pietro Andreone
Anna S.F. Lok
Erwin Sablon
Carmela Cursaro
Munira Hussain
Evelien Libbrecht
Scott K. Fung
Hussain M.
Fung S.
Libbrecht E.
Sablon E.
Cursaro C.
Andreone P.
Lok A.S.
Source :
Journal of clinical microbiology. 44(3)
Publication Year :
2006

Abstract

The INNO-LiPA HBV DR v2 assay is designed to detect hepatitis B virus mutations conveying resistance to lamivudine and adefovir. Our study confirms that this assay can simultaneously detect the presence of lamivudine and adefovir resistance mutations in clinical samples, has a high degree of concordance with sequencing, and can detect mutants earlier.

Details

ISSN :
00951137
Volume :
44
Issue :
3
Database :
OpenAIRE
Journal :
Journal of clinical microbiology
Accession number :
edsair.doi.dedup.....beb2bef7ea49a9b073b81e46ecf6d980