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Sensitive line probe assay that simultaneously detects mutations conveying resistance to lamivudine and adefovir
- Source :
- Journal of clinical microbiology. 44(3)
- Publication Year :
- 2006
-
Abstract
- The INNO-LiPA HBV DR v2 assay is designed to detect hepatitis B virus mutations conveying resistance to lamivudine and adefovir. Our study confirms that this assay can simultaneously detect the presence of lamivudine and adefovir resistance mutations in clinical samples, has a high degree of concordance with sequencing, and can detect mutants earlier.
- Subjects :
- Microbiology (medical)
Hepatitis B virus
Genes, Viral
Mutant
Organophosphonates
Drug resistance
Biology
In Vitro Techniques
medicine.disease_cause
Antiviral Agents
Polymerase Chain Reaction
Sensitivity and Specificity
Hepatitis B, Chronic
Virology
Drug Resistance, Viral
medicine
Adefovir
Humans
Line Probe Assay
Mutation
Base Sequence
Adenine
fungi
Lamivudine
food and beverages
virus diseases
RNA-Directed DNA Polymerase
Hepatitis B
medicine.disease
Molecular biology
digestive system diseases
DNA, Viral
DNA Probes
medicine.drug
Subjects
Details
- ISSN :
- 00951137
- Volume :
- 44
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Journal of clinical microbiology
- Accession number :
- edsair.doi.dedup.....beb2bef7ea49a9b073b81e46ecf6d980