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Oxidative stress response to different exercise intensity with an automated assay: thiol/disulphide homeostasis
- Publication Year :
- 2020
- Publisher :
- Taylor & Francis Ltd, 2020.
-
Abstract
- CETINKAYA, Ayhan/0000-0002-8212-7149 WOS: 000481214300001 PubMed: 31409146 The aim of this study was to investigate the effect of different intensity treadmill exercises on the thiol disulphide homeostasis which is a new marker of oxidative stress in rats. Male albino Wistar rats were randomly divided into four groups as follows: control (CNT), low (LEx), moderate (MEx) and high-intensity exercise (HEx) group. Exercise was performed for 4 weeks. Following completion of the experimental protocol, serum total thiol, native thiol and disulphide concentrations were determined using a novel automated measurement method. Additionally, dynamic disulphide status, reduced thiol, oxidised thiol and thiol oxidation reduction percentage ratios were compared among the groups. Disulphide levels were significantly lower in MEx group and highest in CNT group (p = .047). The lowest oxidised thiol and the highest reduced thiol were determined in CNT group (p = .086; p = .083). These findings indicate that moderate-intensity exercise is more effective in reducing oxidative stress than low and high-intensity exercise. Research Fund of the Sakarya UniversitySakarya University [2017-08-06-030] This work was supported by Research Fund of the Sakarya University. Project Number: 2017-08-06-030.
- Subjects :
- Male
Physiology
030209 endocrinology & metabolism
medicine.disease_cause
03 medical and health sciences
0302 clinical medicine
Physiology (medical)
medicine
Animals
Homeostasis
oxidative stress
Disulfides
Sulfhydryl Compounds
Treadmill
Thiol disulphide homeostasis
Exercise
chemistry.chemical_classification
thiol
General Medicine
Rats
Oxidative Stress
disulphide
chemistry
Biochemistry
030220 oncology & carcinogenesis
Thiol
Exercise intensity
Oxidation-Reduction
Oxidative stress
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....be96f75a09066a3ec9e7f420975aef2e