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Efficient relaxivity enhancement in dendritic gadolinium complexes: effective motional coupling in medium molecular weight conjugates

Authors :
Kanthi Senanayake
David Parker
David A. Fulton
Silvio Aime
Mauro Botta
Mark O'Halloran
Source :
Chemical Communications. :474
Publication Year :
2005
Publisher :
Royal Society of Chemistry (RSC), 2005.

Abstract

Enhancement of the relaxivities of Gd-based MRI contrast agents is achieved by placing the metal ion at the barycentre of the molecular complex in order to improve motional coupling.

Details

ISSN :
1364548X and 13597345
Database :
OpenAIRE
Journal :
Chemical Communications
Accession number :
edsair.doi.dedup.....be8bde3f20926219b016e14c50de4b6d
Full Text :
https://doi.org/10.1039/b413536a