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Quality of reporting of clinical trials in dogs and cats: An update
- Source :
- Journal of Veterinary Internal Medicine, Vol 35, Iss 4, Pp 1957-1971 (2021), Journal of Veterinary Internal Medicine
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Background Comprehensive reporting of clinical trials is essential to allow the trial reader to evaluate the methodological rigor of the trial and interpret the results. Since publication of the updated Consolidated Standards of Reporting Trials (CONSORT) guidelines for reporting of parallel clinical trials in humans, extensions for reporting of abstracts and crossover trials have been published. Objectives To describe the types of trials using dogs and cats published from 2015 to 2020 and to evaluate the quality of reporting of a sample of recently published parallel and crossover trials. Animals None. Methods A comprehensive search was conducted to identify parallel or crossover design clinical trials using dogs and cats published from January 1, 2015 onwards. Quality of reporting was evaluated on a subset of trials published during 2019. The reporting of items recommended in the CONSORT reporting guidelines for abstracts, parallel trials, and crossover trials was evaluated independently by 2 reviewers using standardized forms created for this study. Disagreements among reviewers were resolved by consensus. Results were tabulated descriptively. Results The frequency of reporting of trial features varied from low to high. There remain deficiencies in the quality of reporting of key methodological features and information needed to evaluate and interpret trial results. Conclusions and Clinical Importance There is still a need for authors, peer‐reviewers, and editors to follow reporting guidelines such as CONSORT to maximize the value of clinical trials and to increase confidence in the validity of the trial results.
- Subjects :
- Research Report
medicine.medical_specialty
Consensus
040301 veterinary sciences
media_common.quotation_subject
Veterinary medicine
Standard Article
030204 cardiovascular system & hematology
Cat Diseases
0403 veterinary science
03 medical and health sciences
0302 clinical medicine
Dogs
CONSORT statement
SF600-1100
companion animals
Medicine
Animals
Quality (business)
Medical physics
Therapeutic Trial
Dog Diseases
media_common
General Veterinary
business.industry
Consolidated Standards of Reporting Trials
04 agricultural and veterinary sciences
Reference Standards
Crossover study
Standard Articles
Clinical trial
Cats
SMALL ANIMAL
Clinical Trials, Veterinary as Topic
business
trial reporting
Subjects
Details
- Language :
- English
- ISSN :
- 08916640 and 19391676
- Volume :
- 35
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Journal of Veterinary Internal Medicine
- Accession number :
- edsair.doi.dedup.....be1e9f908e39d229c5695f013b4307eb