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Exercise Training Reverses Gut Dysbiosis in Patients With Biopsy-Proven Nonalcoholic Steatohepatitis: A Proof of Concept Study

Authors :
Jessica Dahmus
Regina Lamendella
Gloriany Rivas
Justin P. Wright
Christopher N. Sciamanna
Rohit Loomba
Jeremy R. Chen See
Kathryn H. Schmitz
Jonathan G. Stine
Breianna L. Hummer
Andrew D. Patterson
Alexa Hughes
Mack T. Ruffin
Source :
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol 19, iss 8, Clin Gastroenterol Hepatol
Publication Year :
2021
Publisher :
eScholarship, University of California, 2021.

Abstract

Nonalcoholic fatty liver disease is the leading cause of liver disease worldwide and can progress to nonalcoholic steatohepatitis (NASH) through physical inactivity and gut dysbiosis.1 Exercise training reverses gut dysbiosis in non-NASH persons with obesity and in NASH animal models.2,3 Consequently, we conducted a proof-of-concept study investigating the effect of exercise training on gut dysbiosis in NASH patients.

Details

Database :
OpenAIRE
Journal :
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol 19, iss 8, Clin Gastroenterol Hepatol
Accession number :
edsair.doi.dedup.....bd534d7f354a412bd3e187ca29f65266