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Serum D‐lactate concentrations in dogs with parvoviral enteritis
- Source :
- Journal of Veterinary Internal Medicine, Vol 34, Iss 2, Pp 691-699 (2020), Journal of Veterinary Internal Medicine
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- Background Dogs infected with canine parvovirus (CPV) have compromised intestinal epithelial barrier integrity. Production of D‐lactate by enteric bacteria may directly reflect disease severity or contribute to metabolic acid‐base status in these dogs. Hypothesis Serum D‐lactate concentration will be increased in CPV dogs compared to healthy controls and correlate with markers of disease severity and acid‐base status. Animals Dogs with CPV undergoing treatment (n = 40) and healthy control dogs (n = 9). Methods Prospective observational study. Dogs with CPV had a baseline and daily CBC, venous blood gas with serum electrolyte concentrations, composite clinical severity score, and serum D‐lactate concentration performed. A single serum D‐lactate measurement was obtained from healthy control dogs. Results The CPV dogs had a higher D‐lactate concentration (mean ± SD) of 469 ± 173 μM compared to controls, 306 ± 45 μM (P
- Subjects :
- medicine.medical_specialty
D‐lactic acid
Enteric bacteria
Standard Article
Gastroenterology
Enteritis
Parvoviridae Infections
Dogs
Internal medicine
medicine
Animals
Dog Diseases
Lactic Acid
Prospective Studies
Acidosis
Epithelial barrier
lcsh:Veterinary medicine
General Veterinary
biology
Parvovirus
business.industry
parvovirus
Canine parvovirus
Venous blood
biology.organism_classification
medicine.disease
Standard Articles
lcsh:SF600-1100
SMALL ANIMAL
acidosis
medicine.symptom
business
D lactate
Subjects
Details
- ISSN :
- 19391676 and 08916640
- Volume :
- 34
- Database :
- OpenAIRE
- Journal :
- Journal of Veterinary Internal Medicine
- Accession number :
- edsair.doi.dedup.....bd3e68a4f3bd33f49279ea5d4c16c012