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MCH and feeding behavior-interaction with peptidic network
- Source :
- Peptides, Peptides, Elsevier, 2009, 30 (11), pp.2045-51. ⟨10.1016/j.peptides.2009.07.008⟩
- Publication Year :
- 2009
-
Abstract
- International audience; Numerous works associate the MCH peptide, and the hypothalamic neurons that produce it, to the feeding behavior and energy homeostasis. It is commonly admitted that MCH is an orexigenic peptide, and MCH neurons could be under the control of arcuate NPY and POMC neurons. However, the literature data is not always concordant. In particular questions about the intrahypothalamic circuit involving other neuropeptides and about the mechanisms through which MCH could act are not yet clearly answered. For example, which receptors mediate a MCH response to NPY or alpha-MSH, does MCH act alone, is there any local anatomical organization within the tuberal LHA? A review of the current literature is then needed to help focus attention on these unresolved and often neglected issues.
- Subjects :
- medicine.medical_specialty
Melanin-concentrating hormone
Physiology
Hypothalamus
Neuropeptide
Biology
MESH: Neuropeptides
Biochemistry
Energy homeostasis
03 medical and health sciences
Cellular and Molecular Neuroscience
chemistry.chemical_compound
0302 clinical medicine
Endocrinology
MESH: Melanins
Hypothalamic Hormones
Orexigenic
Internal medicine
medicine
Animals
Humans
MESH: Animals
[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Neuropeptide Y
MESH: Neuropeptide Y
030304 developmental biology
Melanins
0303 health sciences
MESH: Humans
MESH: alpha-MSH
Neuropeptides
Feeding Behavior
respiratory system
Neuropeptide Y receptor
MESH: Hypothalamus
MESH: Hypothalamic Hormones
Orexin
Pituitary Hormones
MESH: Pituitary Hormones
chemistry
alpha-MSH
MESH: Feeding Behavior
Neuroscience
hormones, hormone substitutes, and hormone antagonists
030217 neurology & neurosurgery
medicine.drug
Subjects
Details
- ISSN :
- 18735169 and 01969781
- Volume :
- 30
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Peptides
- Accession number :
- edsair.doi.dedup.....bd320458fc2ccf60cdbaa44074dc6ef2