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High incidence of ductal closure or narrowing at birth in patients with right ventricular outflow tract obstruction with normal orientation of the ductus arteriosus
- Source :
- Cardiology in the young. 29(1)
- Publication Year :
- 2018
-
Abstract
- BackgroundDuctal patency is mandatory to manage patients with ductal-dependent pulmonary circulation. The aim of this study is to elucidate the morphological and haemodynamic features of ductus arteriosus with right ventricular outflow tract obstruction, and investigate the appropriate perinatal management.Patients and methodsPatients with prenatal diagnosis of right ventricular outflow tract obstruction at our institution between 2010 and 2015 were included in the study. Reverse orientation of the ductus arteriosus is defined as an inferior angle of 90°. We retrospectively reviewed the shape and flow pattern of ductus arteriosus and the clinical characteristics of the cases.ResultsA total of 39 patients were enrolled. The shape was divided into normal orientation (n=15) and reverse orientation (n=24) of the ductus arteriosus. There was no significant difference in the type of oxygen saturation at birth and age at shunt operation between both the groups. However, the median narrowest diameter of ductus arteriosus in the normal orientation group was significantly smaller than that in the reverse orientation group (2.0 [1.0–5.4] versus 3.0 [1.3–4.4] mm, pConclusionsNormal orientation pattern might have high incidence of an early narrowing or closure of ductus arteriosus at birth. The critical patients need careful evaluation by repeated foetal echocardiography and further maternal interventions.
- Subjects :
- congenital, hereditary, and neonatal diseases and abnormalities
medicine.medical_specialty
Hemodynamics
Prenatal diagnosis
030204 cardiovascular system & hematology
Right ventricular outflow tract obstruction
Shunt operation
Ventricular Outflow Obstruction
03 medical and health sciences
0302 clinical medicine
Orientation (mental)
Pregnancy
Ductus arteriosus
Internal medicine
Prenatal Diagnosis
medicine
Humans
In patient
cardiovascular diseases
Ductus Arteriosus, Patent
Retrospective Studies
Cyanosis
business.industry
Incidence
Infant, Newborn
General Medicine
Ductus Arteriosus
medicine.anatomical_structure
030228 respiratory system
Echocardiography
Pediatrics, Perinatology and Child Health
cardiovascular system
Cardiology
Female
High incidence
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 14671107 and 10479511
- Volume :
- 29
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Cardiology in the young
- Accession number :
- edsair.doi.dedup.....bd2a10de981f24f8d6be3770678530d2