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The epidemiology and surveillance of visceral leishmaniasis in the Campania region of Italy. The value of zymodeme typing
The epidemiology and surveillance of visceral leishmaniasis in the Campania region of Italy. The value of zymodeme typing
- Publication Year :
- 1993
-
Abstract
- SummaryAlthough human visceral leishmaniasis (VL) is a notifiable disease in Italy, there is evidence that the actual number of cases is far higher than that notified. A programme for active surveillance of VL in the 14 Italian endemic regions was launched by the Istituto Superiore di Sanità. We report data collected during a 3-year period of active surveillance in Campania, a south Tyrrhenian region covering 4·5% of the Italian territory. Out of 120 clinically suspected cases referred to medical and diagnostic references centres, there were 52 confirmed VL cases (17·3/year), i.e. 10-fold more than previously notified. Most of the infection sites were in rural areas or peripheral districts of towns in hilly parts of Naples province. An epidemic cluster of 10 cases was identified in a microfocus of Caserta province. The biochemical analysis of 23Leishmaniastocks showed a zymodeme composition indicating Campania as an old and well-established focus of VL. The data obtained emphasize that the present notification system for VL in Italy is inadequate.
- Subjects :
- Adult
Male
Veterinary medicine
medicine.medical_specialty
Adolescent
Epidemiology
Allopurinol
Notifiable disease
Antiprotozoal Agents
Disease cluster
Disease Outbreaks
Meglumine
Environmental health
medicine
Organometallic Compounds
Animals
Humans
Leishmania infantum
Child
Skin Tests
Meglumine Antimoniate
biology
Infant, Newborn
Infant
Leishmaniasis
medicine.disease
biology.organism_classification
Isoenzymes
Infectious Diseases
Geography
Visceral leishmaniasis
Italy
Zymodeme typing
Child, Preschool
Population Surveillance
Leishmaniasis, Visceral
Female
Seasons
Rural area
Research Article
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....bcfb1e4eb8e6b558110f81ff70e83d64