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Determinants of delayed diagnosis in Parkinson's disease
- Source :
- Journal of neurology. 260(8)
- Publication Year :
- 2013
-
Abstract
- The early and accurate diagnosis of Parkinson's disease (PD) is the first step towards optimal patient management. The aim of this study was to investigate the major determinants of delayed diagnosis in PD. We recruited a population-representative cohort of 239 newly-diagnosed PD patients who underwent clinical and neuropsychological evaluation. Non-parametric methods were used to define the factors associated with diagnostic delay. The median time from motor symptom onset to primary care physician (PCP) presentation was considerably longer than the time from PCP presentation to PD diagnosis (11 vs. 1 months). Male sex and presenting motor phenotype were independently associated with delayed PCP presentation on Cox regression analysis. Patients presenting with gait disturbance experienced the longest delay, whilst those presenting with tremor had the shortest. In summary, male sex and presenting motor phenotype are key determinants of delayed diagnosis in PD.
- Subjects :
- Male
Pediatrics
medicine.medical_specialty
Neurology
Parkinson's disease
Delayed Diagnosis
Population
Disease
Antiparkinson Agents
Cohort Studies
Sex Factors
Tremor
medicine
Humans
education
Gait Disorders, Neurologic
Aged
Aged, 80 and over
education.field_of_study
Primary Health Care
Proportional hazards model
business.industry
Primary care physician
Parkinson Disease
Middle Aged
medicine.disease
Phenotype
Socioeconomic Factors
Cohort
Physical therapy
Regression Analysis
Female
Neurology (clinical)
business
Cohort study
Subjects
Details
- ISSN :
- 14321459
- Volume :
- 260
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Journal of neurology
- Accession number :
- edsair.doi.dedup.....bcf07ad57d19d1c17b4d6bb242de9602