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Kidney transplant recipients vaccinated before transplantation maintain superior humoral response to SARS‐CoV‐2 vaccine
- Source :
- Clinical Transplantation
- Publication Year :
- 2021
- Publisher :
- John Wiley and Sons Inc., 2021.
-
Abstract
- Majority of transplant recipients did not develop an appreciable humoral response following SARS‐CoV‐2 vaccine, in contrast to dialysis patients and healthy individuals. We analyzed the serologic response to BNT162b2 (Pfizer‐BioNTech) vaccine in a cohort of 19 kidney transplant recipients, vaccinated prior to transplantation, compare to 109 recipients vaccinated after transplantation, and to 39 healthcare workers, by determining the level of anti‐spike antibodies after transplantation. All controls and 17 of 19 (90%) of recipients vaccinated before transplant were seropositive, while only 49 of 109 (45%) recipients vaccinated post‐transplant had positive serology (P
- Subjects :
- medicine.medical_specialty
COVID-19 Vaccines
medicine.medical_treatment
Antibodies, Viral
SARS‐CoV‐2
Serology
COVID‐19
Internal medicine
vaccine
medicine
Humans
Dialysis
Kidney transplantation
BNT162 Vaccine
Aged
Transplantation
biology
business.industry
SARS-CoV-2
COVID-19
Odds ratio
Original Articles
medicine.disease
Kidney Transplantation
Transplant Recipients
Vaccination
surgical procedures, operative
Cohort
biology.protein
Original Article
Antibody
business
Subjects
Details
- Language :
- English
- ISSN :
- 13990012 and 09020063
- Database :
- OpenAIRE
- Journal :
- Clinical Transplantation
- Accession number :
- edsair.doi.dedup.....bce3a694cbe4eb5f95a409ae2b417d27