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Kidney transplant recipients vaccinated before transplantation maintain superior humoral response to SARS‐CoV‐2 vaccine

Authors :
Roni Baruch
Dan Turner
Moshe Shashar
Eugene Katchman
Idit F. Schwartz
Helena Katchman
Doron Schwartz
Inbal Houri
Merav Ben-Yehoyada
Liane Rabinowich
Yaacov Goykhman
Oren Shibolet
Tami Halperin
Ayelet Grupper
Sharon Levy
Source :
Clinical Transplantation
Publication Year :
2021
Publisher :
John Wiley and Sons Inc., 2021.

Abstract

Majority of transplant recipients did not develop an appreciable humoral response following SARS‐CoV‐2 vaccine, in contrast to dialysis patients and healthy individuals. We analyzed the serologic response to BNT162b2 (Pfizer‐BioNTech) vaccine in a cohort of 19 kidney transplant recipients, vaccinated prior to transplantation, compare to 109 recipients vaccinated after transplantation, and to 39 healthcare workers, by determining the level of anti‐spike antibodies after transplantation. All controls and 17 of 19 (90%) of recipients vaccinated before transplant were seropositive, while only 49 of 109 (45%) recipients vaccinated post‐transplant had positive serology (P

Details

Language :
English
ISSN :
13990012 and 09020063
Database :
OpenAIRE
Journal :
Clinical Transplantation
Accession number :
edsair.doi.dedup.....bce3a694cbe4eb5f95a409ae2b417d27