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Children with eosinophilic esophagitis in real life: 10 years' experience with a focus on allergic management
- Source :
- Allergologia et immunopathologia, Allergologia et immunopathologia, 2020, 48 (3), pp.244--250. ⟨10.1016/j.aller.2019.07.013⟩
- Publication Year :
- 2020
- Publisher :
- HAL CCSD, 2020.
-
Abstract
- INTRODUCTION AND OBJECTIVES: Eosinophilic esophagitis (EoE) is frequently miss-diagnosed or overlooked for several years because of the invasiveness of investigations and the non-specificity of symptoms in childhood. Due to the lack of specific recommendations in children, its management remains very heterogeneous, especially concerning allergy testing. The aim of this study is to analyze our population and practices, in comparison with the literature, with a focus on allergic management, to harmonize and optimize our practice. MATERIAL AND METHODS: We included all children with a diagnosis of EoE at the Hospital Femme Mere Enfant, Bron, France. Data were collected via retrospective chart review. RESULTS: 108 patients were included with an average age of 9.5 years. Average delay before diagnosis was 6.65 years. Symptoms varied with age, with a predominance of vomiting (60% of patients), feeding difficulties (72%) and growth difficulties (24%) in children \textless5 years, whereas older children often presented with feeding blockage (64%) and dysphagia (61%). Cough was frequent in our cohort (18.5%), especially in children \textless10 years (38.5% between three and five years). The allergic background was frequent (70.3%) and 80% of our patients benefited from allergy testing. Allergy testing was particularly useful to guide therapy as elimination diet represented an effective treatment in 60% of our patients CONCLUSIONS: Allergy testing has to be harmonized to include major allergens (egg, milk, peanut, fish, wheat, and soy), including prick and patch tests. Allergy-testing based diet seemed to be the best compromise between efficiency and constraints, especially in mono-sensitized patients.
- Subjects :
- Male
Pulmonary and Respiratory Medicine
Pediatrics
medicine.medical_specialty
Arachis
[SDV]Life Sciences [q-bio]
Immunology
Population
Real life
Allergy testing
Feeding difficulty
Feeding and Eating Disorders
03 medical and health sciences
0302 clinical medicine
Chart review
medicine
Humans
Immunology and Allergy
In real life
Child
Eosinophilic esophagitis
education
Skin Tests
Pediatric
education.field_of_study
business.industry
Egg Proteins
General Medicine
Allergens
Milk Proteins
medicine.disease
3. Good health
030228 respiratory system
Child, Preschool
Vomiting
Analysis of practices
Fish
Female
France
medicine.symptom
Deglutition Disorders
business
Food Hypersensitivity
030215 immunology
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Allergologia et immunopathologia, Allergologia et immunopathologia, 2020, 48 (3), pp.244--250. ⟨10.1016/j.aller.2019.07.013⟩
- Accession number :
- edsair.doi.dedup.....bcc761e8d560f1ccb65490dd8226924d