Back to Search
Start Over
The serum level of a novel lipogenic protein Spot 14 was reduced in metabolic syndrome
- Source :
- PLoS ONE, Vol 14, Iss 2, p e0212341 (2019), PLoS ONE
- Publication Year :
- 2019
- Publisher :
- Public Library of Science (PLoS), 2019.
-
Abstract
- Spot 14 (S14) protein is primarily expressed in adipogenic tissues. Compared to wild type, S14 knockout mice had better resistance to diet-induced obesity and glucose tolerance. However, the association between serum S14 level and metabolic variables in humans has never been investigated. The objectives of this study were to evaluate the associations between serum S14 concentrations with components of metabolic syndrome (MetS). A total of 327 subjects were recruited in this cross-sectional study and categorized by presence of MetS. The mean serum levels of S14 were significantly lower in subjects with MetS than those without (87.1±26.3 μg/L vs. 107.3±40.2 μg/L, p
- Subjects :
- Male
0301 basic medicine
Physiology
Peptide Hormones
Gene Expression
Adipose tissue
Blood Pressure
Vascular Medicine
Biochemistry
chemistry.chemical_compound
0302 clinical medicine
Glucose Metabolism
Risk Factors
Immune Physiology
Medicine and Health Sciences
Odds Ratio
Metabolic Syndrome
Innate Immune System
Multidisciplinary
Nuclear Proteins
Middle Aged
Lipids
Cholesterol
Physiological Parameters
Adipose Tissue
Obesity, Abdominal
Cytokines
Carbohydrate Metabolism
Medicine
Female
Adiponectin
Anatomy
Research Article
Adult
medicine.medical_specialty
Science
Immunology
030209 endocrinology & metabolism
03 medical and health sciences
Adipokines
Internal medicine
Genetics
medicine
Humans
Obesity
Triglycerides
Aged
Triglyceride
business.industry
Body Weight
Hypertriglyceridemia
Biology and Life Sciences
Cholesterol, LDL
Odds ratio
Molecular Development
medicine.disease
Hormones
Biological Tissue
Metabolism
Cross-Sectional Studies
Logistic Models
030104 developmental biology
Endocrinology
chemistry
Metabolic Disorders
Immune System
Linear Models
Metabolic syndrome
business
Developmental Biology
Transcription Factors
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 14
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....bcbbbda54e315afb71e89020dfe1f67f