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The Association between the Cross-Sectional Area of the Dural Sac and Low Back Pain in a Large Population: The Wakayama Spine Study
- Source :
- PLoS ONE, PLoS ONE, Vol 11, Iss 8, p e0160002 (2016)
- Publication Year :
- 2016
- Publisher :
- Public Library of Science, 2016.
-
Abstract
- OBJECTIVE:The purpose of this study was to evaluate the relations between the degree of encroachment, measured as the cross-sectional area of the dural sac, and low back pain in a large population. METHODS:In this cross-sectional study, data from 802 participants (247 men, 555 women; mean age, 63.5 years) were analyzed. The measurement of the cross-sectional area of the dural sac from the level of L1/2 to L4/5 was taken using axial T2-weighted images. The minimum cross-sectional area was defined as the cross-sectional area of the dural sac at the most constricted level in the examined spine. Participants were divided into three groups according to minimum cross-sectional area measurement quartiles (less than the first quartile, between the first and third quartiles, and greater than the third quartile). A multivariate logistic regression analysis was used to estimate the association between the minimum cross-sectional area and the prevalence of low back pain. RESULTS:The mean minimum cross-sectional area was 117.3 mm2 (men: 114.4 mm2; women: 118.6 mm2). A logistic regression analysis adjusted for age, sex, body mass index, and other confounding factors, including disc degeneration, showed that a narrow minimum cross-sectional area (smaller than the first quartile) was significantly associated with low back pain (odds ratio, 1.78; 95% confidence interval, 1.13-2.80 compared to the wide minimum cross-sectional area group: minimum cross-sectional area greater than the third quartile measured). CONCLUSION:This study showed that a narrow dural sac cross-sectional area was significantly associated with the presence of low back pain after adjustment for age, sex, and body mass index. Further investigations that include additional radiographic findings and psychological factors will continue to elucidate the causes of low back pain.
- Subjects :
- Male
Cross-sectional study
Physiology
lcsh:Medicine
Dentistry
Intervertebral Disc Degeneration
Logistic regression
Pathology and Laboratory Medicine
Diagnostic Radiology
Body Mass Index
0302 clinical medicine
Mathematical and Statistical Techniques
Spinal Stenosis
Medicine and Health Sciences
Prevalence
Medicine
lcsh:Science
Intervertebral Disc
Musculoskeletal System
Stenosis
Multidisciplinary
Anatomy, Cross-Sectional
Radiology and Imaging
Confounding
Middle Aged
Low back pain
Magnetic Resonance Imaging
Quartile
Physiological Parameters
Physical Sciences
Legs
Regression Analysis
Female
medicine.symptom
Anatomy
Statistics (Mathematics)
Research Article
medicine.medical_specialty
Imaging Techniques
Lower Back Pain
Pain
Surgical and Invasive Medical Procedures
Research and Analysis Methods
03 medical and health sciences
Signs and Symptoms
Diagnostic Medicine
Humans
Statistical Methods
030203 arthritis & rheumatology
business.industry
lcsh:R
Limbs (Anatomy)
Body Weight
Biology and Life Sciences
Odds ratio
Confidence interval
Spine
Surgery
Cross-Sectional Studies
lcsh:Q
Dura Mater
business
Body mass index
Low Back Pain
030217 neurology & neurosurgery
Mathematics
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 11
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....bca0c61b2bedf0d93ca0c38bf72beb59