Additional file 2 of Type 2 diabetes mellitus-associated transcriptome alterations in cortical neurones and associated neurovascular unit cells in the ageing brain

Additional file 2 Fig. S2 Diabetic Complications Network. WGCNA of IMPaLA-generated lists of DEGs enriched in AGE-RAGE signalling in diabetic complications, chemokine signalling, HIF-1 signalling, fluid shear stress and atherosclerosis, and NAFLD pathways in the KEGG database. Hub genes included in the NanoString panel are highlighted in yellow. Targets which were validated by immunohistochemistry are indicated by the asterisks. Two gene products are linked in red, if they participated in the same reaction within a pathway. The strengths of relationships are represented by the intensity of the colour and the thickness of the interconnecting lines. Created using the GeneMANIA plugin for Cytoscape version 3.7.2