KIM127, an antibody that promotes adhesion, maps to a region of CD18 that included cysteine-rich repeats

Authors :: A. Shock
J.T. Romer
Carl G. Figdor
P. E. Stephens
Martyn K. Robinson
S. Ortlepp
M. Spitali
Source :: Cell Adhesion and Communication, 3, 5, pp. 375-384, Cell Adhesion and Communication, 3, 375-384. Harwood acad publ gmbh, Cell Adhesion and Communication, 3, pp. 375-384, Cell Adhesion and Communication, 3, 375-384
Publication Year :: 1995
Abstract: A series of fusion proteins have been generated between human and mouse CD18. These proteins have been used to carry out preliminary mapping studies on a number of anti-CD18 antibodies including KIM127 an antibody that promotes CD18-dependent adhesion. This antibody maps to a region of the CD18 molecule between amino acids 406 and 570 in a region containing cysteine-rich repeats.

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