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A Case-Control Study of Oral Epithelial Proliferative Markers among Sudanese Toombak Dippers Using Micronuclei Assay, Argyrophilic Nucleolar Organizer Region, Papanicolaou and Crystal Violet Methods
- Source :
- Rare Tumors, Rare Tumors, Vol 5, Iss 3, Pp e31-e31 (2013)
- Publication Year :
- 2013
- Publisher :
- SAGE Publications, 2013.
-
Abstract
- The use of Toombak has been reported to play a major role in the etiology of oral cancer in Sudan. The cellular proliferative activity on the oral epithelium of 210 Toombak dippers was assessed by applying the micronuclei frequency, mean argyrophilic nucleolar organizer region (AgNOR) counts, Papanicolaou method, and 1% crystal violet stain. Participants were divided into 3 groups: 200 were apparently healthy individuals, 100 were Toombak users (cases), 100 were non-tobacco users (control) and 10 were patients with oral squamous cell carcinomas. Cytological atypia was identified among 4 (4%). Toombak users and was not found among the control group (P
- Subjects :
- Pathology
medicine.medical_specialty
Histology
crystal violet
Papanicolaou stain
lcsh:RC254-282
Stain
Article
medicine
Atypia
Oral mucosa
Toombak
business.industry
Case-control study
Cancer
oral cancer
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
medicine.disease
Nucleolar Organizer Region
AgNOR
medicine.anatomical_structure
Oncology
micronuclei
Micronucleus test
micronuclei, Toombak, crystal violet, AgNOR, oral cancer
business
Subjects
Details
- ISSN :
- 20363613
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Rare Tumors
- Accession number :
- edsair.doi.dedup.....bc6323f2ac7b0322944f3d83bd7267ed