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Incidental focal FDG uptake in heart is a lighthouse for considering cardiac screening
- Source :
- Annals of Nuclear Medicine. 27:572-580
- Publication Year :
- 2013
- Publisher :
- Springer Science and Business Media LLC, 2013.
-
Abstract
- Cardiac FDG uptake is known to show a variety of patterns under clinical fasting conditions. We hypothesized that focal FDG uptake in the heart (FUH) represents a sign of cardiac disease risk, especially in coronary artery disease (CAD).The aim of this study was to clarify the relationship between FUH and cardiac disease. Cases showing FUH were selected based on comments in diagnostic reports or identification on retrospective review. Quantitative analysis was performed using maximum standardized uptake value (SUVmax), with regions of interest drawn over focal uptake areas in the heart as confirmed by PET/CT and in lateral side of the same slice showing focal FDG uptake. For the 20 patients (11 men, 9 women) with confirmed FUH, coronary artery stenosis or history of treatment for coronary disease was present in 11 patients (55.0 %), and 2 patients showed apical hypertrophy. Mean SUVmax of FUH did not differ significantly between patients with confirmed cardiac disease and those with no evidence of cardiac disease (P = 0.78). FUH suggests a high likelihood of CAD in patients without myocardial symptoms. Cardiac screening or a check of the history of cardiac disease is thus worth considering when FUH is seen incidentally on FDG-PET/CT.
- Subjects :
- Male
medicine.medical_specialty
Heart Diseases
Standardized uptake value
Disease
Muscle hypertrophy
Coronary artery disease
Fluorodeoxyglucose F18
medicine
Humans
Radiology, Nuclear Medicine and imaging
In patient
Aged
Aged, 80 and over
Incidental Findings
PET-CT
medicine.diagnostic_test
business.industry
Myocardium
Fdg uptake
Biological Transport
General Medicine
Middle Aged
medicine.disease
Positron emission tomography
Positron-Emission Tomography
Female
Radiology
Tomography, X-Ray Computed
business
Subjects
Details
- ISSN :
- 18646433 and 09147187
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Annals of Nuclear Medicine
- Accession number :
- edsair.doi.dedup.....bc1f879b0475f7fe95adb58dd90dc86b