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Long-term adult renal graft outcome after ureteric drainage into an augmented bladder or ileal conduit

Authors :
M. G. Thick
D. F. Mirza
Kamal Abusin
Derek Manas
S. M. Bawa
David Rix
M. Mohammed
D Talbot
Source :
Transplant international : official journal of the European Society for Organ Transplantation. 11
Publication Year :
1998

Abstract

Patients with an augmented or diverted urinary system are considered higher risk recipients in view of increased technical problems and infective complications. We studied the long-term renal graft function and survival in patients with a pretransplant ileal conduit or ileal/caecocystoplasty. Between 1986 and 1997, 14 of 1253 (1.1 %) renal transplant recipients had their transplant ureters anastomosed into an abnormal urinary tract. These consisted of ten ileal conduits and four ileal/caecocystoplasties. Median follow up was 42 months (range 1–156). All ten ileal conduits were discharged with a functioning graft. There was one graft loss chronic rejection and one cardiac death. The median creatinine level was 130 mmol/l and 50 % have a urinary infection. All the patients with an ileal/caecocystoplasty were discharged with a functioning graft and these are still functioning; median creatinine of 132 mmol/l and 75 % have a urinary infection. One- and 3-year graft survival was 93 % and 86 %. We conclude that the long-term outcome of renal transplantation in carefully assessed patients with an abnormal urinary tract is satisfactory despite a high incidence of urinary infection.

Details

ISSN :
09340874
Volume :
11
Database :
OpenAIRE
Journal :
Transplant international : official journal of the European Society for Organ Transplantation
Accession number :
edsair.doi.dedup.....bc17320bada6971c2b31c76ea1de153d