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Early post-operative intravenous tacrolimus in pediatric liver transplant recipients is not superior to oral tacrolimus

Authors :
Eri Ogawa
Tarek Abdelazeem Sabra
Yasser Saad-Eldin
Atsushi Yoshizawa
Hideaki Okajima
Shinya Okamoto
Mohamed A. Osman
Shinji Uemoto
Source :
Pediatric transplantation. 23(3)
Publication Year :
2017

Abstract

We aimed to compare the early results of i.v. with p.o. TAC as a primary immunosuppressant in pediatric patients undergoing LT. This retrospective study enrolled 75 children who underwent LT and received TAC-steroid regimens as a primary immunosuppressant between September 2011 and October 2015 at our institution. Thirty-five recipients received TAC i.v. and 40 received TAC p.o. Early results were evaluated and compared, including ACR, EBV, or CMV infection; renal adverse effects; and hospital stay. Comparisons of 90-day post-transplant results showed that the rates of overall viral (74% vs 40% P

Details

ISSN :
13993046
Volume :
23
Issue :
3
Database :
OpenAIRE
Journal :
Pediatric transplantation
Accession number :
edsair.doi.dedup.....bbe2e749aa10c2629bc9052cf7c97fc1