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The Incidence of Heparin-Induced Thrombocytopenias
- Source :
- The International journal of angiology : official publication of the International College of Angiology, Inc. 7(3)
- Publication Year :
- 1998
-
Abstract
- The incidence of heparin-induced thrombocytopenia (HIT) types I and II was investigated retrospectively in 500 heparin-treated patients. In our department of internal medicine 500 patients were treated with unfractionated, middle- or low-molecular heparin (s.c. or i.v.) during 1995 as inpatients. Excluded were patients with other known causes of thrombocytopenia. There were 306 females (61%), mean age 76 years (17–98 years) and 194 males (39%), mean age 73 years (24–93 years). The incidence of HI type I was 4.4% and of HIT type II 0.6% with a positive heparin-induced-platelet-activation test (HIPA test). In addition, HIT type II was suspected in another 1.4% of cases with negative or missing HIPA test. Because of our results on the incidence of HIT type I and type II a close control of thrombocyte count during heparin therapy is necessary. In the case of HIT type II disease, heparin therapy must be stopped immediately.
Details
- ISSN :
- 10611711
- Volume :
- 7
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- The International journal of angiology : official publication of the International College of Angiology, Inc
- Accession number :
- edsair.doi.dedup.....bbc29c6a3a5dafb2113d084c76d437a4