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Mechanical Test Method on the Estimation of the Lubricant Performance by Hyaluronic Acid

Authors :
A. Toshimitsu Yokobori
Toshihiro Hayashi
Takashi Kawaharada
Shigeru Sasaki
Shou Heng Fang
Soubei Watanabe
Shuichi Komatsu
Source :
Bio-Medical Materials and Engineering. 5:117-124
Publication Year :
1995
Publisher :
IOS Press, 1995.

Abstract

Cases with loss of articular cartilage or lowering of articular lubricant performance are frequent among patients afflicted by various gonarthropathies or those fitted with prosthetic joints. The management of such cases has necessitated evaluation studies on the clinical efficacy of using high molecular weight hyaluronic acid as an artificial synovial fluid with a view to improving articular lubricant performance. The proper implementation of such evaluation studies on lubrication performance requires testing methods capable of assessing basic lubricant performance not ouly with respect to articular cartilage alone but also with respect to various other combinations of materials, i.e., lubrication between articular bone and artificial joints, etc. In the present study, first, a simple standard lubricant performance test using several small readily procurable test specimens was de­ vised. Then, this test was employed to evaluate the basic lubricant properties of hyaluronic acid intended for use as artificial synovial fluid. Key Words-mechanical testing, pendulum type friction tester, skeletal joint, hyaluronic acid, lubrication, molecular weight, viscosity

Details

ISSN :
09592989
Volume :
5
Database :
OpenAIRE
Journal :
Bio-Medical Materials and Engineering
Accession number :
edsair.doi.dedup.....bb4619bab9eb3f61264932951c9dc87a
Full Text :
https://doi.org/10.3233/bme-1995-5206