Non-esterified fatty acids of blood serum in type 1 diabetic women during late pregnancy

Using gas chromatography a comparative study of the range and content of individual non-esterified fatty acids in serum of patients with diabetes mellitus type 1 in the third trimester of pregnancy, and healthy pregnant and non-pregnant women has been carried out. In groups of pregnant women there was activation of lipid metabolism, confirmed by corresponding changes in serum biochemical parameters, as well as in the content of non-esterified fatty acids. Intergroup differences in the non-esterified fatty acids were not found. However, there were significant differences between the examined groups in the quantitative content of non-esterified fatty acids.S ispol'zovaniem gazovoĭ khromatografii provedeno sravnitel'noe izuchenie spektra i soderzhaniia individual'nykh neéterifitsirovannykh zhirnykh kislot (NÉZhK) v syvorotke krovi zdorovykh (ZBZh) i bol'nykh sakharnym diabetom 1-go tipa (DBZh) patsientok na tret'em trimestre beremennosti, a takzhe prakticheski zdorovykh neberemennykh zhenshchin (ZZh). V gruppakh beremennykh zhenshchin vyiavlena aktivatsiia lipidnogo metabolizma, chto nashlo svoe otrazhenie kak v biokhimicheskikh pokazateliakh zhirovogo obmena, tak i v soderzhanii NÉZhK. Mezhgruppovykh razlichiĭ v sostave NÉZhK ne obnaruzheno. Mezhdu issleduemymi gruppami vyiavleny sushchestvennye razlichiia v kolichestvennom soderzhanii NÉZhK.