Back to Search
Start Over
Serum Cortisol Concentrations in Dogs with Pituitary‐Dependent Hyperadrenocorticism and Atypical Hyperadrenocorticism
- Source :
- Journal of Veterinary Internal Medicine
- Publication Year :
- 2014
- Publisher :
- John Wiley and Sons Inc., 2014.
-
Abstract
- Background Atypical hyperadrenocorticism (AHAC) is considered when dogs have clinical signs of hypercortisolemia with normal hyperadrenocorticism screening tests. Hypothesis/Objectives To compare cortisol concentrations and adrenal gland size among dogs with pituitary‐dependent hyperadrenocorticism (PDH), atypical hyperadrenocorticism (AHAC), and healthy controls. Animals Ten healthy dogs, 7 dogs with PDH, and 8 dogs with AHAC. Method Dogs were prospectively enrolled between November 2011 and January 2013. Dogs were diagnosed with PDH or AHAC based on clinical signs and positive screening test results (PDH) or abnormal extended adrenal hormone panel results (AHAC). Transverse adrenal gland measurements were obtained by abdominal ultrasound. Hourly mean cortisol (9 samplings), sum of hourly cortisol measurements and adrenal gland sizes were compared among the 3 groups. Results Hourly (control, 1.4 ± 0.6 μg/dL; AHAC, 2.9 ± 1.3; PDH, 4.3 ± 1.5) (mean, SD) and sum (control, 11.3 ± 3.3; AHAC, 23.2 ± 7.7; PDH, 34.7 ± 9.9) cortisol concentrations differed significantly between the controls and AHAC (P
- Subjects :
- Male
medicine.medical_specialty
Adrenocortical Hyperfunction
Hydrocortisone
Cortisol Excess
Standard Article
Atypical Cushing's Syndrome
Dogs
Internal medicine
Adrenal Glands
medicine
Endocrine system
Animals
Dog Diseases
Adrenal
General Veterinary
Adrenal gland
business.industry
Adrenocortical hyperfunction
medicine.disease
Pathophysiology
Standard Articles
medicine.anatomical_structure
Endocrinology
Female
business
Endocrine
Serum cortisol
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 19391676 and 08916640
- Volume :
- 29
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of Veterinary Internal Medicine
- Accession number :
- edsair.doi.dedup.....badccdb33685ea6d23271d23d89277b8