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A study analyzing macular microvasculature features after vitrectomy using OCT angiography in patients with idiopathic macular epiretinal membrane
- Source :
- BMC Ophthalmology, BMC Ophthalmology, Vol 20, Iss 1, Pp 1-8 (2020)
- Publication Year :
- 2020
- Publisher :
- BioMed Central, 2020.
-
Abstract
- Background To evaluate postoperative changes in retinal capillary plexus and to assess contributing factors in postoperative visual improvement using optical coherence tomography angiography (OCT-A) in patients with idiopathic epiretinal membrane (iERM) post membrane removal. Methods Patients scheduled for vitrectomy and membrane peel for iERM were enrolled. 35 subjects were included for this study. OCT-A was used to measure the FAZ related parameters and the superficial and deep capillary plexus layers using 3 mm × 3 mm scans. Measurements were taken before surgery and at every post-surgical follow-up. The unaffected fellow eyes were used as controls. Evaluated factors included: BCVA, vessel density (VD) and retinal thickness (RT) in five regions, FAZ area, FAZ perimeter (PERIM), acircularity index (AI) and foveal vessel density (FD). Results Compared with the control group, the foveal vessel density (FVD) in superficial capillary plexus (SCP) was greater in the epi-retinal membrane group (P p > 0.05). After surgery there was a reduction in the PRVD in SCP. The FVD in DCP increased and the PRVD in DCP decreased at baseline (p p > 0.05). D-value of LogMAR BCVA was positively correlated with pre-op LogMAR BCVA (p p P P Conclusions Vitrectomy and membrane removal led to the decrease of VD in SCP and the increase of PRVD in DCP. Patients with a more severe iERM may receive greater visual improvement with surgery. Trial registration Trial registration number (TRN) and date of registration. ChiCTR2000031289, retrospectively registered, 2020.03.26.
- Subjects :
- Male
medicine.medical_specialty
genetic structures
Fundus Oculi
medicine.medical_treatment
Visual Acuity
Vitrectomy
Perimeter
chemistry.chemical_compound
Oct angiography
lcsh:Ophthalmology
Ophthalmology
Medicine
Humans
In patient
Macula Lutea
Postoperative Period
Macular microvasculature features
Fluorescein Angiography
Aged
Retrospective Studies
Plexus
business.industry
Retinal Vessels
Retinal
Epiretinal Membrane
General Medicine
Optical coherence tomography angiography
Idiopathic macular epiretinal membrane
Middle Aged
medicine.disease
eye diseases
chemistry
lcsh:RE1-994
Microvessels
Female
Epiretinal membrane
business
Retinal thickness
Tomography, Optical Coherence
Research Article
Follow-Up Studies
Subjects
Details
- Language :
- English
- ISSN :
- 14712415
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- BMC Ophthalmology
- Accession number :
- edsair.doi.dedup.....ba83546c50fa7ed8b41663ffa321f3ac