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Exposure to ambient air pollution and risk of childhood cancers: A population-based study in Tehran, Iran
- Source :
- Science of The Total Environment. 646:105-110
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- The relationship between air pollution and childhood cancer is inconclusive. We investigated the associations between exposure to ambient air pollution and childhood cancers in Tehran, Iran. This project included children between 1 and 15 years-of-age with a cancer diagnosis by the Center for the Control of Non Communicable Disease (n = 161) during 2007 to 2009. Controls were selected randomly within the city using a Geographic Information System (GIS) (n = 761). The cases were geocoded based on exact home addresses. Air pollution exposure of cases and random controls were estimated by a previously developed Land Use Regression (LUR) model for the 2010 calendar year. The annual mean concentrations of Particulate Matter ≤ 10 μm (PM10), nitrogen dioxide (NO2) and sulfur dioxide (SO2) in the locations of cancer cases were 101.97 μg/m3, 49.42 ppb and 38.92 ppb respectively, while in the random control group, respective mean exposures were 98.63 μg/m3, 45.98 ppb and 38.95 ppb. A logistic regression model was used to find the probability of childhood cancer per unit increase in PM10, NO2 and SO2. We observed a positive association between exposures to PM10 with childhood cancers. We did, however, observe a positive, but not statistically significant association between NO2 exposure and childhood cancer. Our study is the first to highlight an association between air pollution exposure and childhood cancer risk in Iran, however these findings require replication through future studies.
- Subjects :
- Environmental Engineering
010504 meteorology & atmospheric sciences
Air pollution exposure
Nitrogen Dioxide
Childhood cancer
Air pollution
Iran
010501 environmental sciences
medicine.disease_cause
Logistic regression
01 natural sciences
Air Pollution
Neoplasms
Environmental health
medicine
Humans
Environmental Chemistry
Child
Waste Management and Disposal
0105 earth and related environmental sciences
Air Pollutants
Ambient air pollution
business.industry
Cancer
Environmental Exposure
Non-communicable disease
medicine.disease
Pollution
respiratory tract diseases
Population based study
Particulate Matter
business
Subjects
Details
- ISSN :
- 00489697
- Volume :
- 646
- Database :
- OpenAIRE
- Journal :
- Science of The Total Environment
- Accession number :
- edsair.doi.dedup.....ba31a63c28d4f68cffdb67901592d4bb