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The Role of Toll‐like Receptor (TLR) 2 and TLR4 in the Host Defense against Disseminated Candidiasis
- Source :
- The Journal of Infectious Diseases, 185, 10, pp. 1483-9, Journal of Infectious Diseases, 185, 1483-1489. Univ chicago press, Journal of Infectious Diseases, 185, 10, pp. 1483-1489, The Journal of Infectious Diseases, 185, 1483-9
- Publication Year :
- 2002
- Publisher :
- Oxford University Press (OUP), 2002.
-
Abstract
- Contains fulltext : 208279.pdf (Publisher’s version ) (Closed access) Toll-like receptors (TLRs) represent the main class of pattern-recognition receptors involved in sensing pathogenic microorganisms. The aim of the present study was to assess the role of TLR4 in the defense against Candida albicans infection. The outgrowth of C. albicans was 10-fold higher in TLR4-defective C3H/HeJ mice, compared with that in control C3H/HeN mice (P
- Subjects :
- Chemokine
Neutrophils
medicine.medical_treatment
Cell Count
Receptors, Cell Surface
Biology
Kidney
Mice
Phagocytosis
De rol van cytokinen in de pathofysiologie van koortsende ziekten en in de afweer tegen infecties
Candida albicans
medicine
Animals
Drosophila Proteins
Point Mutation
Immunology and Allergy
Macrophage
Mice, Knockout
Mice, Inbred C3H
Toll-like receptor
Membrane Glycoproteins
Tumor Necrosis Factor-alpha
Toll-Like Receptors
The role of cytokines in the pathophysiology of febrile illnesses and in host defense against infections
Candidiasis
Interleukin
biology.organism_classification
Toll-Like Receptor 2
Corpus albicans
Toll-Like Receptor 4
Infectious Diseases
Cytokine
Immunology
Macrophages, Peritoneal
biology.protein
Tumor necrosis factor alpha
Chemokines
Chemokines, CXC
Interleukin-1
Subjects
Details
- ISSN :
- 15376613 and 00221899
- Volume :
- 185
- Database :
- OpenAIRE
- Journal :
- The Journal of Infectious Diseases
- Accession number :
- edsair.doi.dedup.....ba2caffcdaa097cecb2b509a2529d0e6
- Full Text :
- https://doi.org/10.1086/340511