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Natural killer (NK) cell function in paroxysmal nocturnal hemoglobinuria: A deficiency of NK cells, but not an NK cell deficiency
- Publication Year :
- 2015
- Publisher :
- American Society of Hematology, 2015.
-
Abstract
- To the editor: Treatment of the glycosylphosphatidylinositol (GPI) anchor deficiency paroxysmal nocturnal hemoglobinuria (PNH) has been revolutionized by the use of the anti-C5 antibody eculizumab, which blocks complement-mediated hemolysis and the associated pathology.[1][1],[2][2] In addition to
- Subjects :
- Cytotoxicity, Immunologic
Glycosylphosphatidylinositols
Immunology
Cell
Hemoglobinuria, Paroxysmal
Biochemistry
Cell Degranulation
Cohort Studies
Seizures
hemic and lymphatic diseases
medicine
Humans
Lymphocyte Count
Cytotoxicity
biology
business.industry
Cell Biology
Hematology
Eculizumab
medicine.disease
Cell function
Hemolysis
carbohydrates (lipids)
Killer Cells, Natural
medicine.anatomical_structure
Virus Diseases
Paroxysmal nocturnal hemoglobinuria
biology.protein
lipids (amino acids, peptides, and proteins)
Hemoglobinuria
Disease Susceptibility
Antibody
business
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 00064971
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....ba253d41f05e3602b92a40c9d30a2e92