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Gauging the trends of pseudogenes in plants
- Source :
- Critical Reviews in Biotechnology. 41:1114-1129
- Publication Year :
- 2021
- Publisher :
- Informa UK Limited, 2021.
-
Abstract
- Pseudogenes, the debilitated parts of ancient genes, were previously scrapped off as junk or discarded genes with no functional significance. Pseudogenes have come under scrutiny for their functionality, since recent studies have unveiled their importance in the regulation of their corresponding parent genes and various biological mechanisms. Despite the enormous occurrence of pseudogenes in plants, the lack of experimental validation has contributed toward their unresolved roles in gene regulation. Contrarily, most of the studies associated with gene regulation have been mainly reported for humans, mice, and other mammalian genomes. Consequently, in order to present a cumulative report on plant-based pseudogenes research, an attempt has been made to assemble multiple studies presenting the pseudogene classification, the prediction and the determination of comparative accuracies of various computational pipelines, and recent trends in analyzing their biological functions, and regulatory mechanisms. This review represents the classical, as well as the recent advances on pseudogene identification and their potential roles in transcriptional regulation, which could possibly invigorate the quality of genome annotation, evolutionary analysis, and complexity surrounding the regulatory pathways in plants. Thus, when the ambiguous boundary girdling the pseudogenes eventually recedes on account of their explicit orchestration role, research in flora would no longer saunter compared to that on fauna.
- Subjects :
- 0106 biological sciences
Regulation of gene expression
0303 health sciences
Genome
Pseudogene
General Medicine
Genome project
Biology
Biological Evolution
01 natural sciences
Applied Microbiology and Biotechnology
Mice
03 medical and health sciences
Order (biology)
Gene Expression Regulation
Evolutionary biology
010608 biotechnology
Animals
Functional significance
Identification (biology)
Gene
Pseudogenes
030304 developmental biology
Biotechnology
Subjects
Details
- ISSN :
- 15497801 and 07388551
- Volume :
- 41
- Database :
- OpenAIRE
- Journal :
- Critical Reviews in Biotechnology
- Accession number :
- edsair.doi.dedup.....ba0023b1213ffbb214933cf646a8a558