PReS-FINAL-2132: Defining criteria for high disease activity in juvenile idiopathic arthritis: definition and validation of juvenile arthritis disease activity score cutoffs

Assessment of disease activity is a fundamental component of the clinical evaluation of children with juvenile idiopathic arthritis (JIA) because persistently active disease plays a major role in causing joint damage and physical functional disability. Furthermore, measurement of the level of disease activity over time is important in monitoring the disease course and in assessing the effectiveness of therapeutic interventions.