Back to Search
Start Over
An international collaborative study of 105 new cases of adenomatoid odontogenic tumors
- Source :
- Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 132:327-338
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Objective The aim of this study was to report the clinicopathologic features of 105 new cases of adenomatoid odontogenic tumor (AOT) from Brazil, Guatemala, Mexico, and South Africa. Study Design Clinical and radiographic data were collected from records of 5 oral pathology laboratories, and all cases were microscopically reviewed. Results This series of cases included 36 (34.2%) from South Africa; 33 (31.4%) from Brazil; 23 (21.9%) from Mexico; and 13 (12.3%) from Guatemala. Seventy-two patients (68.5%) were females and 33 patients (31.4%) were males, with an average age of 19.2 years. The tumors predominantly affected the anterior maxilla (48.5%), followed by the anterior mandible (29.5%); posterior mandible (15.2%); and posterior maxilla (6.6%). Sixty-three tumors (63.6%) were follicular, 34 (34.3%) were extrafollicular, and 2 (2%) were peripheral. In most cases, the tumors caused considerable cortical expansion (average size 3.4 cm). Microscopically, most cases showed rosette-like and duct-like structures. Conclusions This is one of the largest case series of AOTs reported in the literature and the first multicenter study involving populations from Latin America and South Africa. In a fifth of the present cases, the posterior regions of the gnathic bones were affected and the tumors demonstrated larger sizes compared with cases occurring in other populations.
- Subjects :
- Adult
Male
medicine.medical_specialty
Anterior maxilla
Odontogenic Tumors
Mandible
Pathology and Forensic Medicine
Ameloblastoma
Young Adult
03 medical and health sciences
0302 clinical medicine
Oral and maxillofacial pathology
medicine
Humans
Radiology, Nuclear Medicine and imaging
Dentistry (miscellaneous)
Back
Posterior mandible
Adenomatoid odontogenic tumor
business.industry
030206 dentistry
medicine.disease
Dermatology
Odontogenic
Multicenter study
030220 oncology & carcinogenesis
Female
Surgery
Oral Surgery
business
Posterior maxilla
Brazil
Subjects
Details
- ISSN :
- 22124403
- Volume :
- 132
- Database :
- OpenAIRE
- Journal :
- Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
- Accession number :
- edsair.doi.dedup.....b9e8b7b449079b65dce3d6ed1c9364ed