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Immunoadsorption for autoimmune encephalitis
- Source :
- Atherosclerosis Supplements. 30:257-263
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- Autoimmune encephalitis is a severe inflammatory disorder of the brain. The discovery that several non-infectious forms of encephalitis are associated with autoantibodies was a breakthrough in the care of this previously untreatable group of patients. The correlation of antibody type and titer with pattern and severity of symptoms was essential for the initiation of immunotherapies. First line therapy consists of steroids, intravenous immunoglobulins, plasma exchange or immunoadsorption. Rapid elimination of autoantibodies using selective immunoadsorption and avoiding the disadvantage of plasma substitution is a pathophysiologically guided therapeutic approach, and has been proven to be an effective therapeutic option as part of multimodal immunotherapy.
- Subjects :
- medicine.medical_treatment
Autoimmunity
Hashimoto Disease
macromolecular substances
030204 cardiovascular system & hematology
03 medical and health sciences
Therapeutic approach
0302 clinical medicine
Internal Medicine
Humans
Medicine
Immunoadsorption
Immunosorbent Techniques
Autoantibodies
Autoimmune encephalitis
Plasma Exchange
biology
business.industry
Autoantibody
General Medicine
Immunotherapy
medicine.disease
Titer
Treatment Outcome
Immunology
biology.protein
Encephalitis
Antibody
Cardiology and Cardiovascular Medicine
business
Biomarkers
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 15675688
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- Atherosclerosis Supplements
- Accession number :
- edsair.doi.dedup.....b99c749c0cf8682309dbebfee52ef79b