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Algorithm proposal based on the C. Diff Quik Chek Complete ICT device for detecting Clostridium difficile infection
- Source :
- Enfermedades infecciosas y microbiologia clinica. 31(2)
- Publication Year :
- 2011
-
Abstract
- To assess a new immunochromatography (ICT) test that detects glutamate dehydrogenase (GDH) antigen and Clostridium difficile toxin A/B simultaneously, and to propose an algorithm for the diagnosis of C. difficile infection (CDI) based on this test.We analysed 970 stool samples. Discrepant results between GDH and toxin A/B were resolved using toxigenic culture as the reference.This test enabled us to obtain a conclusive result in30min in 93.8% of the samples. Among the discrepant results (GDH (+)/Toxin A/B (-)), 41.7% (25/60) were found to be toxigenic C. difficile by toxigenic culture.This test has a high sensitivity and specificity for the diagnosis of CDI.
- Subjects :
- Microbiology (medical)
Antigens, Bacterial
genetic structures
business.industry
Clostridium difficile toxin A
Diff-Quik
Clostridium difficile
Virology
Azure Stains
Chromatography, Affinity
Microbiology
Methylene Blue
Glutamate Dehydrogenase
Xanthenes
Clostridium Infections
Medicine
Humans
business
Algorithm
Algorithms
Subjects
Details
- ISSN :
- 15781852
- Volume :
- 31
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Enfermedades infecciosas y microbiologia clinica
- Accession number :
- edsair.doi.dedup.....b979cdb9d3f7c9c6ab4637657a3bce81