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Extensive Middle Cranial Fossa Arachnoid Cysts and Different Clinical Presentation in Two Patients
- Source :
- Journal of Clinical Research in Pediatric Endocrinology
- Publication Year :
- 2014
- Publisher :
- Galenos Yayinevi, 2014.
-
Abstract
- Arachnoid cysts (ACs), particularly suprasellar cysts, cause a wide spectrum of endocrine disorders. Herein, we report two patients diagnosed with an extensive AC in the middle cranial fossa while being investigated for etiologies of precocious puberty and short stature. One of them required surgery due to his pubertal disorders associated with compression effects of cyst. After surgery, his puberty progression was regressed within one year. On the other hand, surgery was not planned for the second patient considering of his cranial imaging findings and the extremely low incidence of growth hormone (GH) deficiency caused by middle fossa AC (MFAC). We started treatment with recombinant human GH and no complication was found during treatment follow-up. Endocrine disorders associated with MFACs are extremely rare. By presenting with these two cases, we aimed to remain our fellow physcians that ACs can be possibly cause of endocrine disorders. Clinicians should be careful evaluating endocrine disorders because real cause may not be cyst itself but masked by it.
- Subjects :
- Male
medicine.medical_specialty
puberty precocious
Hormone Replacement Therapy
Endocrinology, Diabetes and Metabolism
Puberty, Precocious
Case Report
Middle cranial fossa
Short stature
Endocrinology
Hormone replacement therapy (male-to-female)
Humans
Medicine
Endocrine system
Precocious puberty
Cyst
Child
Growth Disorders
Cranial Fossa, Middle
Human Growth Hormone
business.industry
Infant
Decompression, Surgical
medicine.disease
Magnetic Resonance Imaging
Surgery
Arachnoid Cysts
Treatment Outcome
medicine.anatomical_structure
Pediatrics, Perinatology and Child Health
Etiology
Extensive arachnoid cyst
Growth hormone deficiency
medicine.symptom
Complication
business
Biomarkers
Subjects
Details
- ISSN :
- 13085727
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Research in Pediatric Endocrinology
- Accession number :
- edsair.doi.dedup.....b963fde3a084cf69803f5ddbe98a8860