Neutrophil count and percentage: potential independent prognostic indicators for advanced cancer patients in a palliative care setting

// Weiwei Zhao 1,2,* , Peng Wang 2,3,* , Huixun Jia 2,4 , Menglei Chen 1 , Xiaoli Gu 1 , Minghui Liu 1 , Zhe Zhang 1 , Wenwu Cheng 1,2 and Zhenyu Wu 5 1 Center for Biomedical Statistics, Fudan University Shanghai Cancer Center, Shanghai, China 2 Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China 3 Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, China 4 Center for Biomedical Statistical, Fudan University Shanghai Cancer Center, Shanghai, China 5 Department of Biostatistics, School of Public Health, Key Laboratory of Public Health Safety and Collaborative Innovation Center of Social Risks Governance in Health, Fudan University, Shanghai, China * These authors have contributed equally to this work Correspondence to: Zhenyu Wu, email: // Wenwu Cheng, email: // Keywords : neutrophil count, neutrophil percentage, prognostic value, advanced cancer, palliative care Received : November 15, 2016 Accepted : March 09, 2017 Published : March 22, 2017 Abstract The purpose of this study was to evaluate the count and percentage of neutrophils as prognostic indicators in advanced cancer patients undergoing palliative care. 378 consecutive patients receiving treatment at the palliative care unit of Fudan University Shanghai Cancer Center between July 2013 and October 2015 were reviewed. In 106 of these patients, the data were extended during the follow-up. The cut-off values selected for the neutrophil count and percentage were 8.0×10 9 /L and 85%, respectively. Both a high pretreatment neutrophil count ( HR = 1.828, 95% CI: 1.409~2.371, P