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Obstructive Sleep Apnea as a Risk Factor for Atrial Fibrillation: A Meta-Analysis
- Source :
- Journal of sleep disorders & therapy
- Publication Year :
- 2018
- Publisher :
- OMICS Publishing Group, 2018.
-
Abstract
- Objectives: To conducted a meta-analysis assessing the relationship between Obstructive Sleep Apnea (OSA) and the risk of Atrial Fibrillation (AF).Methods: We searched PUBMED, Medline, and Cochrane Library using the keywords “atrial fibrillation”, “obstructive sleep apnea” and “sleep disordered breathing (SDB)”. All subjects included had established diagnosis of OSA/SDB. We then compared the occurrence of AF versus no AF. Analysis done with Comprehensive Meta- Analysis package V3 (Biostat, USA).Results: A total of 579 results were generated. Duplicates were removed and 372 records were excluded based on irrelevant abstracts, titles, study design not consistent with the stated outcome, or full-text unavailable. Twelve studies meeting the inclusion criteria were reviewed in full-text; 2 of these articles were eventually removed due to unconfirmed OSA diagnostic modality, and one was also removed based on a control group inconsistent with the other studies. Therefore, a total of 9 studies were included (n=19,837). Sample sizes ranged from n=160 patients to n=6841 patients. The risk of AF was found to be higher among OSA/SDB versus control group (OR; 2.120, C.I: 1.845- 2.436, Z; 10.598 p
- Subjects :
- Cardiac arrhythmias
medicine.medical_specialty
Sleep Apnea
MEDLINE
030204 cardiovascular system & hematology
Cochrane Library
Article
03 medical and health sciences
0302 clinical medicine
Internal medicine
Atrial Fibrillation
medicine
Risk factor
Prospective cohort study
business.industry
Sleep apnea
Atrial fibrillation
medicine.disease
nervous system diseases
respiratory tract diseases
3. Good health
Obstructive sleep apnea
Meta-analysis
Health
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 21670277
- Database :
- OpenAIRE
- Journal :
- Journal of Sleep Disorders & Therapy
- Accession number :
- edsair.doi.dedup.....b8f1de0ed51055252b1b825a3ab984b3