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Theranostic Nanosystems for Targeted Cancer Therapy
- Source :
- Nano today. 23
- Publication Year :
- 2019
-
Abstract
- Nanomaterials have revolutionized cancer imaging, diagnosis, and treatment. Multifunctional nanoparticles in particular have been designed for targeted cancer therapy by modulating their physicochemical properties to be delivered to the target and activated by internal and/or external stimuli. This review will focus on the fundamental “chemical” design considerations of stimuli-responsive nanosystems to achieve favorable tumor targeting beyond biological barriers and, furthermore, enhance targeted cancer therapy. In addition, we will summarize innovative smart nanosystems responsive to external stimuli (e.g., light, magnetic field, ultrasound, and electric field) and internal stimuli in the tumor microenvironment (e.g., pH, enzyme, redox potential, and oxidative stress).
- Subjects :
- Tumor microenvironment
Tumor targeting
business.industry
medicine.medical_treatment
Multifunctional nanoparticles
Biomedical Engineering
Cancer therapy
Pharmaceutical Science
Bioengineering
Nanotechnology
02 engineering and technology
Cancer imaging
010402 general chemistry
021001 nanoscience & nanotechnology
01 natural sciences
Article
0104 chemical sciences
Targeted therapy
Medicine
General Materials Science
0210 nano-technology
business
Biotechnology
Subjects
Details
- ISSN :
- 17480132
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Nano today
- Accession number :
- edsair.doi.dedup.....b8d5a91ff4507f582ed4d15d1021d64b