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Establishment of induced pluripotent stem cell line (GSPHi001-A) from a 6-year old female with nephrotic syndrome

Authors :
Haiyan Zhao
Mei Tan
Xin Gao
Hui Deng
Weijing Cui
Xia Gao
Source :
Stem Cell Research, Vol 41, Iss, Pp-(2019)
Publication Year :
2019

Abstract

Peripheral blood mononuclear cells (PBMCs) were collected from a 6-year-old female child who was clinically diagnosed as primary nephrotic syndrome (NS) with hormone resistance. An iPSC line was successfully established by the Sendai-virus (SeV) delivery system. The iPS-19 (GSPHi001-A) expressed pluripotent markers, exhibited a normal karyotype and differentiated towards three germ layers. The iPSC line might offer a potentially useful tool for investigating mechanisms of primary NS, drug testing and gene therapy studies.

Details

ISSN :
18767753
Volume :
41
Database :
OpenAIRE
Journal :
Stem cell research
Accession number :
edsair.doi.dedup.....b8c636cc558a25e87c07a551f801a03a