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Establishment of induced pluripotent stem cell line (GSPHi001-A) from a 6-year old female with nephrotic syndrome
- Source :
- Stem Cell Research, Vol 41, Iss, Pp-(2019)
- Publication Year :
- 2019
-
Abstract
- Peripheral blood mononuclear cells (PBMCs) were collected from a 6-year-old female child who was clinically diagnosed as primary nephrotic syndrome (NS) with hormone resistance. An iPSC line was successfully established by the Sendai-virus (SeV) delivery system. The iPS-19 (GSPHi001-A) expressed pluripotent markers, exhibited a normal karyotype and differentiated towards three germ layers. The iPSC line might offer a potentially useful tool for investigating mechanisms of primary NS, drug testing and gene therapy studies.
- Subjects :
- Nephrotic Syndrome
Genetic enhancement
Induced Pluripotent Stem Cells
Reproducibility of Results
Karyotype
Cell Biology
General Medicine
Germ layer
Biology
medicine.disease
Peripheral blood mononuclear cell
Cell Line
lcsh:Biology (General)
Immunology
medicine
Humans
Female
Induced pluripotent stem cell
Child
lcsh:QH301-705.5
Ipsc line
Nephrotic syndrome
Developmental Biology
Hormone
Subjects
Details
- ISSN :
- 18767753
- Volume :
- 41
- Database :
- OpenAIRE
- Journal :
- Stem cell research
- Accession number :
- edsair.doi.dedup.....b8c636cc558a25e87c07a551f801a03a