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Safety and efficacy of vismodegib in patients aged ≥65 years with advanced basal cell carcinoma
- Source :
- Oncotarget, vol 7, iss 46, Oncotarget
- Publication Year :
- 2016
- Publisher :
- Impact Journals, LLC, 2016.
-
Abstract
- Because many patients with unresectable basal cell carcinoma (BCC) are aged ≥65 years, this study explores the efficacy and safety of vismodegib in these patients with locally advanced (la) or metastatic (m) basal cell carcinoma (BCC) in the ERIVANCE BCC trial and the expanded access study (EAS).We compared patients aged ≥65 years to patients aged
- Subjects :
- Male
Gerontology
Skin Neoplasms
Pyridines
Basal Cell
Best Overall Response
030207 dermatology & venereal diseases
0302 clinical medicine
vismodegib
80 and over
Anilides
Cancer
Aged, 80 and over
locally advanced basal cell carcinoma
Age Factors
Middle Aged
Combined Modality Therapy
Treatment Outcome
Oncology
030220 oncology & carcinogenesis
Female
Research Paper
Signal Transduction
medicine.drug
medicine.medical_specialty
Clinical Trials and Supportive Activities
Oncology and Carcinogenesis
Locally advanced
Vismodegib
Antineoplastic Agents
Hedgehog pathway inhibitor
03 medical and health sciences
basal cell carcinoma
Clinical Research
Internal medicine
medicine
Humans
Hedgehog Proteins
Basal cell carcinoma
In patient
Adverse effect
Neoplasm Staging
Aged
business.industry
Prevention
Carcinoma
medicine.disease
Vismodegib 150 MG
age
Carcinoma, Basal Cell
Neoplasm staging
business
Subjects
Details
- ISSN :
- 19492553
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Oncotarget
- Accession number :
- edsair.doi.dedup.....b8b55dbaeb76e128dddef175b701c822