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Metal-free cascade synthesis of unsymmetrical 2-aminopyrimidines from imidazolate enaminones
- Source :
- RSC advances. 11(39)
- Publication Year :
- 2021
-
Abstract
- A convenient metal-free synthesis of unsymmetrical 2-aminopyrimidines from imidazolate enaminones has been developed. In this procedure, various structural 2-aminopyrimidines, as well as 4,5-dihydroisoxazol-5-ols and pyrazoles were synthesized in moderate to excellent yields. A plausible mechanism was also proposed for the cascade reaction. This method represents an effective strategy towards the synthesis of unsymmetrical 2-aminopyrimidines.
Details
- ISSN :
- 20462069
- Volume :
- 11
- Issue :
- 39
- Database :
- OpenAIRE
- Journal :
- RSC advances
- Accession number :
- edsair.doi.dedup.....b85f79eb1913001b923f082185ece6e5