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Antibiotics in periodontal therapy: advantages and disadvantages
- Source :
- Journal of clinical periodontology. 17(7 ( Pt 2))
- Publication Year :
- 1990
-
Abstract
- Antibiotic treatment of periodontitis aims at eradicating or controlling specific pathogens. Prime candidates for antibiotic therapy are patients with recently diagnosed active periodontitis or a history of recurrent disease who fail to stabilize following mechanical/surgical therapy. Since a variety of microbes with differing antimicrobial susceptibility profiles may cause periodontitis, selection of antimicrobial agents should be based on proper microbial diagnosis and sensitivity testing, as well as consideration of the patient's medical status. The risk of treating chemotherapeutically solely on the basis of clinical features, radiographic findings or a limited microbiological analysis, is failure to control the pathogens or overgrowth of new pathogens. A review of published papers reveals that appropriate systemic antibiotic therapy may enhance healing in patients with recent or high risk of periodontal breakdown. Systemic antibiotic therapy seems more predictable than topical administration in eradicating periodontal pathogens from deep periodontal pockets. Several promising antimicrobial agents for periodontitis treatment need testing in placebo-controlled, double-blind, randomized clinical trials.
- Subjects :
- Periodontitis
medicine.medical_specialty
Gingival and periodontal pocket
Bacteria
business.industry
medicine.drug_class
Antibiotics
Dentistry
medicine.disease
Antimicrobial
law.invention
Anti-Bacterial Agents
Systemic antibiotics
Randomized controlled trial
law
Recurrent disease
medicine
Periodontics
Humans
In patient
Intensive care medicine
business
Subjects
Details
- ISSN :
- 03036979
- Volume :
- 17
- Issue :
- 7 ( Pt 2)
- Database :
- OpenAIRE
- Journal :
- Journal of clinical periodontology
- Accession number :
- edsair.doi.dedup.....b80b0d3a5c989c6209a940d878f39338