Back to Search
Start Over
Synthesis of Polysubstituted Trifluoromethylpyridines from Trifluoromethyl-α,β-ynones
- Source :
- The Journal of Organic Chemistry. 85:924-933
- Publication Year :
- 2019
- Publisher :
- American Chemical Society (ACS), 2019.
-
Abstract
- A novel and efficient method for synthesis of polysubstituted trifluoromethylpyridine derivatives by the Bohlmann-Rahtz heteroannulation reaction is described, which use trifluoromethyl-α,β-ynones as trifluoromethyl building blocks to react with β-enamino esters or β-enamino ketones in the presence of ZnBr
Details
- ISSN :
- 15206904 and 00223263
- Volume :
- 85
- Database :
- OpenAIRE
- Journal :
- The Journal of Organic Chemistry
- Accession number :
- edsair.doi.dedup.....b7eae2ad1c3f3b64533583f6687ebde9
- Full Text :
- https://doi.org/10.1021/acs.joc.9b02873