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Clinical Characteristics and Outcomes of Patients with Culture-Negative Pyogenic Spondylitis according to Empiric Glycopeptide Use
- Source :
- Infection & Chemotherapy
- Publication Year :
- 2019
- Publisher :
- The Korean Society of Infectious Diseases and Korean Society for Chemotherapy, 2019.
-
Abstract
- BACKGROUND The optimal choice of antibiotics is challenging in culture-negative pyogenic spondylitis (PS). The empiric use of glycopeptides is suggested depending on various risk factors, although clinical data are sparse. This study aimed to analyze the clinical characteristics and outcomes of patients with culture-negative PS and evaluate the effect of empiric glycopeptide use on clinical outcomes in these patients. MATERIALS AND METHODS Data on the characteristics, treatment, and outcomes of 175 patients diagnosed with PS were retrospectively obtained from the electronic database of a tertiary referral hospital from 2009 to 2016. Patients with negative culture results were grouped by the duration of glycopeptide treatment: glycopeptide therapy
- Subjects :
- medicine.medical_specialty
Culture
Pyogenic spondylodiscitis
Glycopeptide
Group B
03 medical and health sciences
0302 clinical medicine
Pharmacotherapy
Interquartile range
Antibiotics
Internal medicine
medicine
Pharmacology (medical)
030212 general & internal medicine
Prospective cohort study
Spondylitis
0303 health sciences
medicine.diagnostic_test
030306 microbiology
business.industry
medicine.disease
Infectious Diseases
Erythrocyte sedimentation rate
Population study
Original Article
business
Subjects
Details
- Language :
- English
- ISSN :
- 20926448 and 20932340
- Volume :
- 51
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Infection & Chemotherapy
- Accession number :
- edsair.doi.dedup.....b7bad6c4d13e68686b0cba591685fcc2