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Positive association of alcohol consumption with incidence of hypertension in adults aged 40 years and over: Use of repeated alcohol consumption measurements
- Source :
- Clinical Nutrition. 39:3125-3131
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- Managing alcohol consumption may be an effective way of preventing hypertension, which is an important modifiable risk factor for cardiovascular diseases. However, there is little evidence on the temporal relationship between alcohol consumption and incidence of hypertension. We investigated the prospective association between repeated measures of alcohol consumption and hypertension incidence among Korean adults aged 40 and over.This study included a total of 4989 participants that were not taking antihypertensive drugs and had normal blood pressure (BP) (systolic 140 mmHg and diastolic 90 mmHg). We used three measures of alcohol consumption (baseline, most recent, and average) as exposures and compared the three approaches. Using a modified Poisson regression model with a robust error estimator, we estimated incidence rate ratios (IRRs) and 95% confidence intervals (CIs) for hypertension.Over a total of 17,689 person-years (average 3.5 years of follow-up), 574 incident cases of hypertension were identified. In multivariable models, consuming ≥30 ml/d of alcohol was associated with a risk of hypertension among men (IRR = 1.72, 95% CI = 1.20-2.48, p trend = 0.017 for baseline alcohol consumption; IRR = 1.69, 95% CI = 1.23-2.33, p trend = 0.005 for the most recent alcohol consumption; IRR = 1.49, 95% CI = 1.09-2.03, p trend = 0.014 for average alcohol consumption). After additional adjustment for baseline BP the positive association remained only when the most recent alcohol consumption measure was used. There was no significant association between alcohol consumption and hypertension among women, and no interaction effect between alcohol consumption and baseline BP levels on incidence of hypertension (all p interaction 0.05) existed.Alcohol consumption, especially consuming ≥30 ml/d, may be positively linked with incidence risk of hypertension among men.
- Subjects :
- Adult
Male
0301 basic medicine
Alcohol Drinking
Blood Pressure
030209 endocrinology & metabolism
Alcohol
Rural Health
Critical Care and Intensive Care Medicine
Risk Assessment
03 medical and health sciences
chemistry.chemical_compound
Sex Factors
0302 clinical medicine
Risk Factors
Environmental health
Republic of Korea
Humans
Medicine
Prospective Studies
Risk factor
Prospective cohort study
Aged
030109 nutrition & dietetics
Nutrition and Dietetics
business.industry
Incidence
Incidence (epidemiology)
Age Factors
Repeated measures design
Middle Aged
Health Surveys
Blood pressure
chemistry
Hypertension
Female
business
Alcohol consumption
Subjects
Details
- ISSN :
- 02615614
- Volume :
- 39
- Database :
- OpenAIRE
- Journal :
- Clinical Nutrition
- Accession number :
- edsair.doi.dedup.....b7ba8ca50705c9ff4d98de12b24bc8a3