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Outcomes following repeat exenteration for locally advanced pelvic malignancy
- Source :
- Colorectal Disease. 23:646-652
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- AIM This study aims to assess surgical outcomes and survival following first, second and third pelvic exenterations for pelvic malignancy. METHOD Consecutive patients undergoing pelvic exenteration for pelvic malignancy at a quaternary referral centre from January 1994 and December 2017 were included. Demographics and surgical outcomes were compared between patients who underwent first, second and third pelvic exenterations by generalized mixed modelling with repeated measures. Survival was assessed using Cox proportional hazards models and Kaplan-Meier plots. RESULTS Of the 642 exenterations reviewed, 29 (4.5%) were second and 6 (0.9%) were third exenterations. Patients selected for repeat exenteration were more likely to have asymptomatic local recurrences detected on routine surveillance (P
- Subjects :
- medicine.medical_specialty
medicine.medical_treatment
Locally advanced
Asymptomatic
03 medical and health sciences
Postoperative Complications
0302 clinical medicine
medicine
Humans
Pelvic Neoplasms
Proportional Hazards Models
Retrospective Studies
Pelvic exenteration
Proportional hazards model
business.industry
Gastroenterology
Margins of Excision
Repeated measures design
Cancer
medicine.disease
Pelvic Exenteration
Surgery
Treatment Outcome
030220 oncology & carcinogenesis
Pelvic malignancy
030211 gastroenterology & hepatology
Neoplasm Recurrence, Local
medicine.symptom
Complication
business
Subjects
Details
- ISSN :
- 14631318 and 14628910
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Colorectal Disease
- Accession number :
- edsair.doi.dedup.....b77c6ae1eba0789228c664c716cc56eb