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Hypothermic machine perfusion preservation after controlled donor cardiac death reduce delayed graft function
- Source :
- European Urology Open Science, Vol 19, Iss, Pp e1597-e1598 (2020), Dipòsit Digital de la UB, Universidad de Barcelona
- Publication Year :
- 2020
- Publisher :
- Elsevier, 2020.
-
Abstract
- Introduction & Objectives: in Spain kidneys after controlled cardiac death (cDCD) has increased over the years. This group present a high incidence of DGF. Graft quality optimization has been the major interest over the last decade. The aim of this study is to evaluate de benefit of hypothermic machine perfusion (HMP) in reducing de delayed graft function (DGF) and primary non-function (PNF) compared to cold storage in cDCD. Other parameters are evaluated: 99mTc-MAG-3 scintigraphy TFS (tubular function slope) and ultrasound (US) resistive index (RI) 24-48 hours after surgery, rejection rate, duration of DGF. Materials & Methods: We are conducting a randomized prospective study since April 2017. We select all cDCD from one single institution, Hospital Universitari de Bellvitge, and we randomize 1:1 to cold storage and HMP. Data from donors, surgery, HMP, and post-operatory are collected; and analysed.
- Subjects :
- medicine.medical_specialty
Machine perfusion
business.industry
Urology
Perfusion (Physiology)
Ronyó
Perfusió (Fisiologia)
Hipotèrmia
Hypothermia
Kidney
lcsh:Diseases of the genitourinary system. Urology
lcsh:RC870-923
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
lcsh:RC254-282
Delayed Graft Function
Spain
Internal medicine
medicine
Cardiology
Espanya
business
Subjects
Details
- Language :
- English
- ISSN :
- 26661683
- Volume :
- 19
- Database :
- OpenAIRE
- Journal :
- European Urology Open Science
- Accession number :
- edsair.doi.dedup.....b75cb26c9be4790296d39035a0db4c42