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Hypothermic machine perfusion preservation after controlled donor cardiac death reduce delayed graft function

Authors :
Natalia Romero Martínez
Francesc Vigués Julià
Jaume Mora Salvador
Edoardo Melilli
Maria Fiol Riera
Begoña Etcheverry Giadrosich
L. Riera
José Francisco Suárez-Novo
Source :
European Urology Open Science, Vol 19, Iss, Pp e1597-e1598 (2020), Dipòsit Digital de la UB, Universidad de Barcelona
Publication Year :
2020
Publisher :
Elsevier, 2020.

Abstract

Introduction & Objectives: in Spain kidneys after controlled cardiac death (cDCD) has increased over the years. This group present a high incidence of DGF. Graft quality optimization has been the major interest over the last decade. The aim of this study is to evaluate de benefit of hypothermic machine perfusion (HMP) in reducing de delayed graft function (DGF) and primary non-function (PNF) compared to cold storage in cDCD. Other parameters are evaluated: 99mTc-MAG-3 scintigraphy TFS (tubular function slope) and ultrasound (US) resistive index (RI) 24-48 hours after surgery, rejection rate, duration of DGF. Materials & Methods: We are conducting a randomized prospective study since April 2017. We select all cDCD from one single institution, Hospital Universitari de Bellvitge, and we randomize 1:1 to cold storage and HMP. Data from donors, surgery, HMP, and post-operatory are collected; and analysed.

Details

Language :
English
ISSN :
26661683
Volume :
19
Database :
OpenAIRE
Journal :
European Urology Open Science
Accession number :
edsair.doi.dedup.....b75cb26c9be4790296d39035a0db4c42