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The Culture of Biosafety, Biosecurity, and Responsible Conduct in the Life Sciences: A Comprehensive Literature Review
- Source :
- Appl Biosaf
- Publication Year :
- 2018
- Publisher :
- Mary Ann Liebert Inc, 2018.
-
Abstract
- INTRODUCTION: Managing biological risks requires an organizational culture that holistically ensures the biosafety, biosecurity, and biocontainment of infectious disease agents and toxins, in addition to conducting science in a responsible manner, complying with relevant laws, regulations, guidelines, and policies, as well as emphasizing norms, values, and beliefs of the entire life sciences profession. METHODS: Drawing upon the Federal Experts Security Advisory Panel's (FESAP's) 2014 recommendation to “strengthen a culture that emphasizes biosafety, laboratory biosecurity, and responsible conduct in the life sciences,” we undertook a comprehensive literature review of the culture of biosafety, biosecurity, and responsible conduct in the life sciences, including metrics by which to evaluate interventions at the organizational level. RESULTS: We identified 4031 unique citations published from January 2001 to January 2017 by searching the MEDLINE/PubMed, Scopus, Web of Science, and Global Health databases. In addition, a subset of 326 articles was reviewed in full. DISCUSSION: We found that while there were discussions in the literature about specific elements of culture (management systems, leadership and/or personnel behavior, beliefs and attitudes, or principles for guiding decisions and behaviors), there was a general lack of integration of these concepts, as well as limited information about specific indicators or metrics and the effectiveness of training or similar interventions. CONCLUSION: We concluded that life scientists seeking to foster a culture of biosafety and biosecurity should learn from the substantial literature in analogous areas such as nuclear safety and security culture, high-reliability organizations, and the responsible conduct of research, among others.
- Subjects :
- 021110 strategic, defence & security studies
Health, Toxicology and Mutagenesis
Biosecurity
0211 other engineering and technologies
Public Health, Environmental and Occupational Health
Organizational culture
Review Article
06 humanities and the arts
02 engineering and technology
Management, Monitoring, Policy and Law
0603 philosophy, ethics and religion
Biocontainment
Biosafety
Infectious disease (medical specialty)
Engineering ethics
060301 applied ethics
Business
Biotechnology
Subjects
Details
- ISSN :
- 24701246 and 15356760
- Volume :
- 24
- Database :
- OpenAIRE
- Journal :
- Applied Biosafety
- Accession number :
- edsair.doi.dedup.....b75be31ebd7d1c3bf5050ed8f134b7d8