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Drinking of maté and the risk of cancers of the upper aerodigestive tract in Latin America: a case–control study
- Source :
- Cancer Causes & Control. 21:1799-1806
- Publication Year :
- 2010
- Publisher :
- Springer Science and Business Media LLC, 2010.
-
Abstract
- Cancers of the upper aerodigestive tract (UADT: oral cavity, oropharynx, hypopharynx, larynx, esophagus) have high incidence rates all over the world and they are especially frequent in some parts of Latin America. In this study, we have evaluated the role of the consumption of maté, a hot herb-based beverage, based on 1168 UADT squamous-cell carcinoma cases and 1,026 frequency-matched controls enrolled from four centers in Brazil and Argentina. The effect of maté drinking on the risk of head-and-neck cancers was borderline significant. A significant effect was observed only for cancer of the esophagus (OR 3.81 (95% CI 1.75-8.30)). While duration of maté drinking was associated with the risk of all UADT cancers, the association with cumulative maté consumption was restricted to esophageal cancer (p-value of linear trend 0.006). The analyses of temperature at which maté was drunk were not conclusive. The increased risk associated with maté drinking was more evident in never-smokers and never-alcohol drinkers than in other individuals. Our study strengthens the evidence of an association between maté drinking and esophageal cancer; the hypothesis of an association with other UADT cancers remains to be clarified. © 2010 Springer Science+Business Media B.V.
- Subjects :
- Adult
Male
Cancer Research
medicine.medical_specialty
Esophageal Neoplasms
Argentina
Drinking
Gastroenterology
Beverages
Ilex paraguariensis
Internal medicine
upper aerodigestive tract
Epidemiology
medicine
Carcinoma
Humans
Multicenter Studies as Topic
Esophagus
Aged
Aged, 80 and over
business.industry
Head and neck cancer
Pharynx
Case-control study
Cancer
Middle Aged
Esophageal cancer
medicine.disease
Latin America
medicine.anatomical_structure
Oncology
Drinking of maté
Head and Neck Neoplasms
Case-Control Studies
Carcinoma, Squamous Cell
Female
business
Brazil
Demography
Subjects
Details
- ISSN :
- 15737225 and 09575243
- Volume :
- 21
- Database :
- OpenAIRE
- Journal :
- Cancer Causes & Control
- Accession number :
- edsair.doi.dedup.....b73608e0523a1ebec0b45c853d78e5f4