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Red blood cell distribution width-standard deviation but not red blood cell distribution width-coefficient of variation as a potential index for the diagnosis of iron-deficiency anemia in mid-pregnancy women
- Source :
- Open Life Sciences, Vol 16, Iss 1, Pp 1213-1218 (2021), Open Life Sciences
- Publication Year :
- 2021
- Publisher :
- Walter de Gruyter GmbH, 2021.
-
Abstract
- The aim of this study was to compare the diagnostic values of red blood cell distribution width-coefficient of variation (RDW-CV) and red blood cell distribution width-standard deviation (RDW-SD) in mid-pregnancy women with iron deficiency anemia (IDA). To obtain the results, 115 mid-pregnancy women with IDA, defined as the IDA group, and 142 healthy mid-pregnancy women, selected as the control group, were enrolled in this study. Hematological parameters and ferritin concentrations in the serum were analyzed. The efficiency of RDW-CV and RDW-SD to distinguish IDA from mid-pregnancy women was evaluated using receiver operating characteristic (ROC) curves. The RDW-SD value in the IDA group was significantly higher than that in the control group (p < 0.05), while the RDW-CV value did not differ between them (p = 0.84). Significantly negative correlations were found between RDW-CV (r = −0.297, p = 0.001), RDW-SD (r = −0.404, p = 0.000), and serum ferritin in the IDA group but not in the control group. For the diagnosis of IDA, RDW-CV and RDW-SD produced areas under the ROC curves of 0.58 and 0.84. To conclude, our results suggest that RDW-SD, but not RDW-CV, can be used as a diagnostic index of IDA for mid-pregnancy women.
- Subjects :
- medicine.medical_specialty
QH301-705.5
Coefficient of variation
Biology
Gastroenterology
General Biochemistry, Genetics and Molecular Biology
Standard deviation
Mid pregnancy
hemic and lymphatic diseases
Internal medicine
medicine
Biology (General)
iron deficiency anemia
General Immunology and Microbiology
Receiver operating characteristic
General Neuroscience
nutritional and metabolic diseases
rdw standard deviation
Red blood cell distribution width
medicine.disease
mid-pregnancy women
Ferritin
Red blood cell
medicine.anatomical_structure
Iron-deficiency anemia
biology.protein
General Agricultural and Biological Sciences
rdw coefficient of variation
Research Article
Subjects
Details
- ISSN :
- 23915412
- Volume :
- 16
- Database :
- OpenAIRE
- Journal :
- Open Life Sciences
- Accession number :
- edsair.doi.dedup.....b6e1ecbb799c184dc3f4f06500d77be0